Jaguar Tree, or macambo, is the common name for the Theobroma Bicolor. The tree is close related to the Theobroma Cacao from which chocolate is made. Although the ripe seeds contain pharmacologically active substances like theobromine, the admixture of macambo in rapé refers in all probability not to the ground seeds, but to the addition of ashes of the inner bark. Many unscientific sources suggest otherwise and refer to the pharmacological aspects of macambo in rapé, though this information can not be affirmed in ethnobotanical literature. The ashes produced by burning the bark serve as an alkaloid activator. By bringing the pH values of rapé down with the alkaline ashes, the psychoactive compounds of the snuff are more easily absorbed through the mucous membranes.
- Rätsch, The Encyclopedia of Psychoactive Plants (2005)
Stanfill, Stephen B et al. “Comprehensive chemical characterization of Rapé tobacco products: Nicotine, un-ionized nicotine, tobacco-specific N’-nitrosamines, polycyclic aromatic hydrocarbons, and flavor constituents” Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association vol. 82 (2015): 50-8.