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Peganum harmala Extract | 10:1 – 20:1 and 50:1 | Syrian rue | Esfand | Harmine | Harmaline

Our Peganum harmala extract (full spectrum) is available in three different potencies. Made from Iranian Syrian rue seeds and made in a professional laboratory.




Peganum harmala Extracts | 10:1 – 20:1 and 50:1 | Syrian rue | Esfand | Harmine | Harmaline

We offer Peganum harmala extract (full spectrum) in three forms:

  • 10x/10:1 Peganum harmala extract contains 0.68 % alkaloids
  • 25x/25:1 Peganum harmala extract contains 2.40 % alkaloids
  • 50x/50:1 Peganum harmala extract contains 6.20 % alkaloids

Also take a look at our whole Peganum harmala seeds and pure alkaloid extract.

Native Use

Due to its resemblance to the unrelated Rue plant, Peganum harmala is commonly known as Syrian Rue. The plant is believed to originate from Iran and India but its distribution includes North Africa, Spain, Italy and Turkey, and many countries of the middle east. Due to the diversity of cultures and languages Peganum harmala has many names. They include Harmel, Esfand, Aspand, Wild Rue, Syrian Rue, African Rue, Harmed, Techepak (Ladakhi), Tukhm-i-isfand, and Uzarih (Turkish).

In Iran, the seeds of Peganum harmala are burned in great quantity with the belief that it will keep misfortune at bay (it works against the “evil eye”) with the extra ability to protect the land from diseases. Moreover, the shamans of the Himalayas use rue seeds as incense to create a magical mood. It is said that the inhalation creates a trance of union with a goddess that bestows powers of healing.

As a remedy, it has been used to make women’s childbirth labor much easier and to relieve pain during their monthly period. In Asia, rue seeds have been used to treat stomach troubles, heart diseases, and the herb has also been used to heal skin disorders. In addition, a strong decoction is traditionally used as a tranquilizer. Peganum harmala is also used for its alleged antibiotic, antiparasitic, and analgesic effects. It has often been applied by women who were looking to induce miscarriages.

In Asia, the plant has been used as a dye plant, as a remedy in folk medicine, and as a prolific aphrodisiac as well. In Iran, the plant has had a lot of religious significance. In the Koran, it is documented that “every root, every leaf of harmel, is watched over by an angel who waits for a person to come in search of healing.”


This succulent, bright green perennial shrub is blessed with abundant leaves that grow from the root. The bush can grow up to 1 meter tall but is usually found growing up to about 30cm high. Its branches are smooth and spread up to over 1 meter. The leaves average about 60cm long and then branch off into segments that are long and narrow. The beautiful white flower of the Peganum harmala blossoms June-August and decorates the vibrant green plant. The herb grows in harsh semi-arid conditions and has been used for millennia in every culture where the plant was present.

Scientific Information

The plant is popular in Middle Eastern and North African areas among healers. The alkaloids contained in the plant, including the seeds, are monoamine oxidase inhibitors that go by the name of harmine and harmaline. 

Read More

Moloudizargari, Milad et al. “Pharmacological and therapeutic effects of Peganum harmala and its main alkaloids.” Pharmacognosy reviews vol. 7,14 (2013): 199-212. doi:10.4103/0973-7847.120524

Mina, Cheraghi Niroumand et al. “Medicinal properties of Peganum harmala L. in traditional Iranian medicine and modern phytotherapy: a review.” Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan vol. 35,1 (2015): 104-9. doi:10.1016/s0254-6272(15)30016-9


We strongly believe in the power of natural plant medicines and related products to make a positive contribution towards physical, mental and spiritual health and healing.

Whilst we take great care to verify and reference all information presented on this website we are expressing our own opinions, beliefs, personal experience and indigenous wisdom and knowledge. We are not publishing scientifically proven facts. All information is provided in good faith “as is” with no warranty or guarantee.

Our products are not certified by the US Food and Drug Administration (FDA) nor by Health Canada, for human consumption. They are sold for incense and soap making purposes, decorative purposes and/or legitimate ethnobotanical research. Our products are not sold or intended for human consumption. The information given about the plants is for academic purposes only and not intended to be used medically. Wakingherbs.com, its suppliers, agents, employees and distributors cannot be held accountable for any misuse of the products offered.

Colours of the product may vary; as we sell natural products we don’t make photos of every new batch. Sometimes the exact form of the products can differ from that of the photo.

We guarantee the authenticity of our products and the correct botanical title.

Unfortunately, due to legislation we cannot ship this product to the following countries: Australia, Canada, France, Norway, Poland, Reunion, South Africa,, Ukraine and Taiwan.


“We always plant more than we harvest.”

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